Relais Il Santissimo is set in Turi and features a spa and wellness centre, a garden and a terrace. A hot tub is available for guests, along with a sauna. The accommodation provides room service, ticket service and organising tours for guests. At the hotel, rooms are fitted with a desk, a TV and a private bathroom. The rooms have a wardrobe. Relais Il Santissimo offers a hammam. Cycling is among the activities that guests can enjoy near the accommodation. Bari is 30 km from Relais Il Santissimo, while Alberobello is 25 km from the property. The nearest airport is Bari Karol Wojtyla Airport, 42 km from the property.